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Constraints
Reference: none
Live demo idle
Pitch mode is active. This view keeps the live sequence path and the benchmark-backed wedge surfaces, while hiding operator and audit clutter. Press P to exit.
Experiment mode is active. This view keeps the live sequence path, refine controls, animation, reference, hotspots, binding sites, and ensemble while hiding pitch and benchmark surfaces. Press E to exit.
Sequence
Auto reference prefers ESMFold. Quality mode improves ensemble refinement and, when the local topology runner is active, uses the topology-first auto profile.
Examples
Tools
Interactive Refine
Use -1 for all spans, otherwise choose a zero-based editable span index.
Editable Segments
Quick nudge
Quick rotate
Quick twist
Quick bend
Quick stretch
Local axis shift
Shape presets
Freeze anchor residues, optionally define editable spans, then translate, rotate or twist the movable segment before a short CTT3 preview relax.
Display

Folding Animation

Step: 0/0 RMSD: --Å
Speed: 1x

Reference

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Demo Briefing

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This is the partner-first talk track for a live pitch: benchmark-backed seed first, then the two delivery surfaces, then downstream state utility and routed refine evidence.

Product Wedge Overview

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Product claim stays narrow: direct external is the default seed, while our advantage starts in downstream state ranking and target-actionable refine routing.

Benchmark Surface

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State Support Surface

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This layer is the explicit downstream ranking wedge: stronger target-state utility after the external seed, not a claim about better static structure.

External Refine Dashboard

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Primary product path stays on benchmark-backed controller output. Layer-by-layer refine research remains available below for audit and traceability.

Partner Demo Bundle

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Use this after the live demo: README narrative, shortlist CSVs, and manifest-backed copied artifacts for partner follow-up.
Refine Layer Audit Canonical controller stays above; per-layer research surfaces remain here for benchmark drill-down.

Layer Audit Overview

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External Refine Research

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Move-Class Refine

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Self-Intersection Refine

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Self-Intersection Policy

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Move-Policy Refine

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Controller Refine

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Annulus Refine

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Annulus Policy

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Corridor Refine

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Corridor Uniqueness

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Corridor Policy

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Window Policy Refine

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Supervisory Refine

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Supervisory Map

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Personal Variant Surface Off the critical pitch path. Expand only if you need the personal follow-up layer.
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Allosteric Hotspots

Fold a protein to see hotspots

Binding Sites

Fold a protein to see sites

Experiment Mixer

Select a hotspot and a pocket volume to build a joint refine experiment.
Suggested experiments will appear when both hotspots and pocket volumes are available.
Saved experiments will appear here after you pin a cue pair.
Save two experiments and mark them as A/B to compare cue coverage and refine deltas.

Ensemble

Member: 0/50
Ready to fold!
Flexible
Rigid
Hotspot